Altered metabolism of bile acids correlates with clinical parameters and the gut microbiota in patients with diarrhea-predominant irritable bowel syndrome

Figure 2 Fecal bacterial structures of patients with diarrhea-predominant irritable bowel syndrome and healthy controls. A: Chao1 index in the irritable bowel syndrome with predominant diarrhea (IBS-D) group and the healthy control (HC) group, Chao1 index was decreased significantly in the IBS-D group; B and C: Weighted and unweighted principal coordinate analysis of fecal bacterial in the IBS-D and HC groups, both differed significantly between the two groups. Boxes indicate the interquartile range; lines inside the boxes indicate the medians; the two whiskers indicate the maximum and minimum of the data; the points outside the box indicate outliers. PCoA: Principal coordinate analysis.