Retrospective Study
Copyright ©The Author(s) 2020.
World J Gastroenterol. Nov 28, 2020; 26(44): 7022-7035
Published online Nov 28, 2020. doi: 10.3748/wjg.v26.i44.7022
Table 4 Comparison of the changes in the carcinoembryonic antigen level after curative resection
VariablesGroup A (n = 27)Group B (n = 43)Group C (n = 65)P value
Name of surgery0.272
Low anterior resection15 (55.6%)22 (51.2%)43 (66.2%)
Others112 (44.4%)21 (48.8%)22 (33.8%)
Differentiation0.781
Well–Moderate8 (29.6%)13 (30.2%)16 (24.6%)
Poorly + others219 (70.4%)30 (69.8%)49 (75.4%)
Lymphovascular invasion0.444
No22 (81.5%)35 (81.4%)58 (89.2%)
Yes5 (18.5%)8 (18.6%)7 (10.8%)
Perineural invasion0.005
No21 (77.8%)38 (88.4%)64 (98.5%)
Yes6 (22.2%)5 (11.6%)1 (1.5%)
Postoperative T stage< 0.001
0–22 (7.4%)11 (25.6%)38 (58.5%)
3–425 (92.6%)32 (74.4%)27 (41.5%)
Postoperative N stage0.538
N015 (55.6%)27 (62.8%)44 (67.7%)
N+12 (44.4%)16 (37.2%)21 (32.3%)
Postoperative M stage0.002
M024 (88.9%)43 (100%)65 (100%)
M13 (11.1%)00
Postoperative TNM stage< 0.001
003 (7.0%)25 (38.5%)
I2 (7.4%)5 (11.6%)8 (12.3%)
II13 (48.1%)19 (44.2%)11 (16.9%)
III9 (33.3%)16 (37.2%)21 (32.3%)
IV3 (11.1%)00
CEA on postoperative day 73.7 (2.8-5.2)1.6 (1.1-2.2)1.1 (0.7-1.7)< 0.001
Tumor regression grade< 0.001
01 (3.7%)3 (7.0%)26 (40.0%)
17 (25.9%)23 (53.5%)18 (27.7%)
211 (40.7%)14 (32.6%)17 (26.2%)
38 (29.6%)3 (7.0%)4 (6.2%)
Good response (TRG 0,1)0.003
TRG 0, 18 (29.6%)26 (60.5%)44 (67.7%)
TRG 2, 319 (70.4%)17 (39.5%)21 (32.3%)
Pathologic complete response< 0.001
pCR (-)27 (100%)41 (95.3%)40 (61.5%)
pCR (+)02 (4.7%)25 (38.5%)