Stress granules in colorectal cancer: Current knowledge and potential therapeutic applications

Figure 2 The molecular landscape underlying stress granules formation in colorectal cancer. Stress granules (SGs) assembly in colorectal cancer cells is associated with several alterations in the expression of proteins involved in SG nucleation or clearance. The stress-related conditions within the tumor microenvironment and various antitumor agents can further promote SGs assembly. Several SG-associated proteins (RNA-binding proteins or others) contribute to various cancer-related processes such as cell cycle progression, apoptosis inhibition, angiogenesis, and chemoresistance. Illustrations were retrieved from Servier Medical art (https://smart.servier.com/). SG: Stress granules.