Efficacy of a Chinese herbal formula on hepatitis B e antigen-positive chronic hepatitis B patients

doi:10.3748/wjg.v26.i30.4501

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 26, Issue 30

This Article

Academic Content and Language Evaluation of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (6387)

All Articles published online

The chart showing PDF series, WORD series, HTML series, Figures (1-7) series, Tables (1-7) series.

Item

Count

PDF

398

WORD

143

HTML

3368

Figures (1-7)

238

Tables (1-7)

195

Sum=4342

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

566

Download

1479

Sum=2045

Aug 14, 2020 (publication date) through Jun 6, 2024

Times Cited of This Article

Times Cited (5)

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Clinical Trials Study

World J Gastroenterol. Aug 14, 2020; 26(30): 4501-4522
Published online Aug 14, 2020. doi: 10.3748/wjg.v26.i30.4501

Table 4 Baseline characteristics of all study patients

Variable	Treatment (ICE) group (n = 199)	Control group(n = 196)	χ²/t/ Z	P value
Age (mean ± SD), yr	38.51 ± 7.63	38.90 ± 7.54	-0.904	0.366^a
Range	30-65	30-63
Sex, n (%)			0.013	0.910^b
Male	128 (64.3)	125 (63.8)
Female	71 (35.7)	71 (36.2)
Regions (N)			2.796	0.593^b
Eastern	30 (14.42)	28 (14.97)
Western	22 (10.58)	18 (9.63)
Southern	89 (42.79)	69 (36.90)
Northern	40 (19.23)	48 (25.67)
Central	27 (12.98)	24 (12.83)
Smoking			0.491	0.484^b
Yes	57 (28.64)	50 (25.51)
No	142 (71.36)	146 (74.49)
Alcohol consumption			3.626	0.057^b
Yes	18 (9.05)	30 (15.31)
No	181 (90.95)	166 (84.69)
Genotype			0.522	0.770^b
B	99 (49.75)	93 (47.45)
C	90 (45.23)	95 (48.47)
D	10 (5.02)	8 (4.08)
Genealogy of hepatocellular carcinoma	2 (1.00)	3 (1.53)	0.000	0.986^b
Clinical course (mean ± SD) week	90.21 ± 22.40	86.69 ± 27.20	-1.607	0.108^a
Liver function (mean ± SD)
ALT, IU/L	29.29 ± 8.19	30.12 ± 6.32	1.126	0.261^c
AST, IU/L	24.86 ± 7.53	25.79 ± 6.19	1.340	0.181^c
TB, μmol/L	14.34 ± 3.25	13.98 ± 4.15	0.961	0.337^c
HBV DNA baseline level, (%)			0.154	0.695^b
2 to < 5 log10 IU/mL	0 (0)	0 (0)
5 to < 7 log10 IU/mL	14 (2.01)	12 (1.02)
7to < 9 log10 IU/mL	185 (97.99)	184 (98.98)
HBsAg (mean ± SD), log10 IU/mL	3.86 ± 0.52	3.89 ± 0.42	-0.758	0.449^a
HBeAg (mean ± SD), SCO/mL	1138.18 ± 423.99	1158.40 ± 401.86	-0.393	0.695^a
HBeAb (mean ± SD), SCO/mL	38.43 ± 14.28	40.01 ± 12.15	-0.904	0.366^a
Histological scores
Knodell (HAI), n (%)	168 (84.40)	156 (79.60)	0.010	0.922^b
≥ 4	60 (35.71)	55(35.26)
< 4	108 (64.29)	101 (64.74)
Ishak (FIB), n (%)			0.035	0.851^b
≥ 2	67 (39.90)	60 (38.46)
< 2	101 (60.10)	96 (61.54)

^a: Mann-Whitney U test;

^b: Chi-square test;

^c: t-test. ICE: Invigorating kidney and clearing away the heat and expelling superficial evils; SD: Standard deviation; ALT: Alanine aminotransferase; AST: Aspartate transaminase; TB: Total bilirubin; HBV: Hepatitis B virus; HBsAg: Hepatitis B virus surface antigen; HBeAg: Hepatitis B virus e antigen; HBeAb: Hepatitis B virus e antibody.

Citation: Xing YF, Wei CS, Zhou TR, Huang DP, Zhong WC, Chen B, Jin H, Hu XY, Yang ZY, He Q, Jiang KP, Jiang JM, Hu ZB, Deng X, Yang F, Li FY, Zhao G, Wang LC, Mi YQ, Gong ZJ, Guo P, Wu JH, Shi WQ, Yang HZ, Zhou DQ, Tong GD. Efficacy of a Chinese herbal formula on hepatitis B e antigen-positive chronic hepatitis B patients. World J Gastroenterol 2020; 26(30): 4501-4522
URL: https://www.wjgnet.com/1007-9327/full/v26/i30/4501.htm
DOI: https://dx.doi.org/10.3748/wjg.v26.i30.4501