Circulating exosomal miRNAs as potential biomarkers for Barrett's esophagus and esophageal adenocarcinoma

Figure 2 Function of exosomal microRNAs in recipient cells. The RNA molecules in exosomes are cell-specific and tissue-specific. MicroRNAs (miRNAs) can interact with the mRNA 3'-untranslated region via their seed sequence and then interfere with the expression of target genes post-transcriptionally to regulate physiological and pathological processes, such as cell proliferation, differentiation, migration, and apoptosis. miRNA: microRNA.