Serrated polyps of the colon and rectum: Remove or not?

Table 2 Rate of dysplasia within sessile serrated lesions, % (95%CI)

Size	Right colon	Left colorectum	Total
≤ 5 mm	0 (0-5.0)	0 (0-25.9)	0 (0-4.2)
6-9 mm	5.9 (2.2-12.5)	6.3 (0.2-30.2)	6.0a (2.4-11.9)
≥ 10 mm	14.1 (8.6-21.3)	8.3 (0.2-38.5)	13.6bc (8.4-20.4)
Total	8.3 (5.4-12.1)	5.3 (0.6-17.7)	8.0 (5.3-11.5)

We histopathologically analyzed 326 sessile serrated lesions. The overall rate of dysplasia (conventional adenoma-like dysplasia and/or serrated dysplasia) within sessile serrated lesions was 8.0% (26/326). This rate significantly increased as the lesion size increased (≤ 5 mm: 0%; 6-9 mm: 6.0%; ≥ 10 mm: 13.6%) but exhibited no significant difference between the right colon and left colorectum.

^aP < 0.05 vs ≤ 5 mm,

^bP < 0.01 vs ≤ 5 mm, and

^cP < 0.05 vs 6-9 mm, the χ² test or Fisher’s exact test.