Optimal proximal resection margin distance for gastrectomy in advanced gastric cancer

Table 1 The basic demographics and clinicopathologic characteristics of patients who underwent distal and total gastrectomy with curative intent for gastric adenocarcinoma, n (%)

Variables	Distal gastrectomy (n = 859)	Total gastrectomy (n = 659)
Age (yr; median) at operation	60 (23-87)	57 (22-86)
Sex
Male	603 (70.2)	441 (66.9)
Female	256 (29.8)	218 (33.1)
BMI (kg/m2, median)	23.2 (16.0-36.2)	23.4 (13.4-36.0)
ASA
1	246 (28.6)	213 (32.3)
2	571 (66.5)	427 (64.8)
3	39 (4.5)	17 (2.6)
4	3 (0.3)	2 (0.3)
Tumor location
Upper 1/3	8 (0.9)	266 (40.4)
Middle 1/3	225 (26.2)	320 (48.6)
Lower 1/3	626 (72.9)	73 (11.1)
Reconstruction
Billroth I	610 (71.0)
Billroth II	137 (15.9)
RYGJ	112 (13.0)
RY		659 (100.0)
Bormann classification
I	14 (1.6)	14 (2.1)
II	162 (18.9)	66 (10.0)
III	660 (76.8)	499 (75.7)
IV	23 (2.7)	80 (12.1)
Tumor size (cm, median)	5.0 (0.8-18)	6.0 (0.7-24)
CLN	27 (15-75)	30 (15-106)
PLN	2 (0-49)	3 (0-101)
T stage
T2	288 (33.5)	110 (16.7)
T3	370 (43.1)	310 (47.0)
T4a	195 (22.7)	226 (34.3)
T4b	6 (0.7)	13 (2.0)
N stage
N0	308 (35.9)	203 (30.8)
N1	181 (21.1)	110 (16.7)
N2	173 (20.1)	128 (19.4)
N3a	159 (18.5)	133 (20.2)
N3b	38 (4.4)	85 (12.9)
AJCC stage
Stage I	155 (18.0)	66 (10.0)
Stage II	336 (39.1)	235 (35.7)
Stage III	368 (42.8)	358 (54.3)
PRM (cm; median)	4.8 (0.3-17)	3.5 (0.1-18.5)
DRM (cm; median)	3.2 (0.2-19)	9.4 (0.3-27)
Histology
Differentiated	351 (40.9)	192 (29.1)
Undifferentiated	508 (59.1)	467 (70.9)
Lymphovascular invasion	413 (48.1)	360 (54.6)
Perineural invasion	368 (42.8)	344 (52.2)
Recurrence	220 (25.6)	251 (38.1)
Locoregional recurrence	60	41
Hematogenous metastasis	74	83
Extra-abdominal LN metastasis	2	1
Peritoneal metastasis	74	1
Mixed	10	17

RYGJ: Roux-en-Y gastrojejunostomy; RY: Roux-en-Y esophagojejunostomy; CLN: Total number of collected lymph nodes; PLN: Total number of positive lymph nodes; PRM: Proximal resection margin; DRM: Distal resection margin; AJCC: American Joint Committee on Cancer.