Folic acid attenuates high-fat diet-induced steatohepatitis via deacetylase SIRT1-dependent restoration of PPARα

doi:10.3748/wjg.v26.i18.2203

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 26, Issue 18

This Article

Academic Content and Language Evaluation of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (9695)

All Articles published online

The chart showing PDF series, WORD series, HTML series, Figures (1-6) series, Tables (1-2) series.

Item

Count

PDF

534

WORD

198

HTML

5386

Figures (1-6)

314

Tables (1-2)

228

Sum=6660

Featured Article

The chart showing Browse series, Download series.

Item

Count

Browse

520

Download

675

Sum=1195

Publishing Process of This Article

Item

Count

Browse

755

Download

1085

Sum=1840

May 14, 2020 (publication date) through Apr 24, 2024

Times Cited of This Article

Times Cited (25)

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Basic Study

World J Gastroenterol. May 14, 2020; 26(18): 2203-2220
Published online May 14, 2020. doi: 10.3748/wjg.v26.i18.2203

Table 1 Primer sequences for real-time quantitative polymerase chain reaction

Gene name	Forward sequence	Reverse sequence
TNF-α	TGCCTCAGCCTCTTCTCATT	GAGCCCATTTGGGAACTTCT
IL-6	AGTTGCCTTCTTGGGACTGA	CCTCCGACTTGTGAAGTGGT
IL-1β	GAAGTCAAGACCAAAGTGG	TGAAGTCAACTATGTCCCG
CCR2	CACCGTATGACTATGATGATG	CAGGAGAGCAGGTCAGAGAT
p47phox	GCCCAAAGATGGCAAGAATA	ATGACCTCAATGGCTTCACC
p67phox	AGCAGAAGAGCAGTTAGCATTGG	TGCTTTCCATGGCCTTGTC
p22phox	GTAGATGCCGCTCGCAATGGCCAG	ATGGGGCAGATCGAGTGGGCCATGT
gp91phox	CTGAGCGAATTGTACGTG	CTTATCACAGCCACAAGC
αSMA	TGTGCTATGTCGCTCTGGAC	CCAATGAAAGATGGCTG GAA
TGFβ1	ATTCCTGGCGTTACCTTGG	AGCCCTGTATTCCGTCTCCT
Col1a1	TGTTCAGCTTTGTGGACCT	CAGCTGACTTCAGGGATGT
Col2a1	ACCTCAGGGTGTTCAAGGTG	CGGATTCCAATAGGACCAGA
Col3a1	GGTGGCTTTCAGTTCAGCTATG	GTCTTGCTCCATTCACCAGTGT
MAT1A	CAATGTGCTCGTGGCTCTGGAG	TCCTCTGTCTCGTCAGTGGCATAG
ALDH1L1	GCACGGCTCCATCATCTACCATC	GTCATCTGGAAGCACCTCACACTC
SREBP1c	CCAGCCTTTGAGGATAACCA	TGCAGGTCAGACACAGGAAG
SCD	AGCTGGTGATGTTCCAGAGG	CAAGAAGGTGCTGACGAACA
ACACA	GAATATCCAGATGGCCGAGA	CCTTCTGCTCTGGCAAGTTC
FASN	GCCTAACACCTCTGTGCAGT	GGCAATACCCGTTCCCTGAA
PPARγ	ACAAGAGCTGACCCAATGGT	GGCTCTTCATGTGGCCTGTT
ACADL	ACTCCGCCTCCGCTTCCATG	TACCACCGTAGATCGGCTGAACTC
FABP1	GTCTGCCTGAGGACCTCATCCAG	TCATGGTCTCCAGTTCGCACTCC
CPT1α	CCACGAAGCCCTCAAACAGA	CACACCCACCACCACGATAA
FATP2	CACGACAGAGTTGGAGACACCTTC	CCGATGCGACCTTCATGACCTG

TNF-α: Tumor necrosis factor alpha; IL: Interleukin; CCR2: Chemokine receptor C-C chemokine receptor type 2; αSMA: α-smooth muscle actin; TGFβ1: Transforming growth factor beta 1; Col1a1: Collagen type I alpha 1; Col2a1: Collagen type II alpha 1; Col3a1: Collagen type III alpha 1; MAT1A: Methionine adenosyltransferase 1A; SREBP1c: Sterol regulatory element binding transcription protein 1c; SCD: Stearoyl-CoA desaturase; ACACA: Acetyl-CoA carboxylase; FASN: Fatty acid synthase; PPARγ: Peroxisome proliferator-activated receptor gamma; ACADL: Long-chain specific acyl-CoA dehydrogenase; FABP1: Fatty acid binding protein 1; CPT1α: Carnitine palmitoyltransferase 1A; FATP2: Fatty acid transport protein 2.

Citation: Xin FZ, Zhao ZH, Zhang RN, Pan Q, Gong ZZ, Sun C, Fan JG. Folic acid attenuates high-fat diet-induced steatohepatitis via deacetylase SIRT1-dependent restoration of PPARα. World J Gastroenterol 2020; 26(18): 2203-2220
URL: https://www.wjgnet.com/1007-9327/full/v26/i18/2203.htm
DOI: https://dx.doi.org/10.3748/wjg.v26.i18.2203