Targeted and immune therapies for hepatocellular carcinoma: Predictions for 2019 and beyond

doi:10.3748/wjg.v25.i7.789

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Feb 21, 2019; 25(7): 789-807
Published online Feb 21, 2019. doi: 10.3748/wjg.v25.i7.789

Table 7 Results of TACTICS trial[30]

	TACE with sorafenib median (M)	TACE alone median (M)	HR (95% CI)	P value
PFS	25.2	13.5	0.59 (0.41-0.87)	0.006
TTUP	26.7	20.6	0.57 (0.36-0.92)	0.02
TTP	26.7	16.4	0.54 (0.35-0.83)	0.005
TTVI	31.3	4.0	0.26 (0.09-0.75)	0.005
TTEHS	15.7	6.9	0.21 (0.06-0.70)	0.006
TTSP	22.5	6.3	0.31 (0.15-0.63)	0.001

TACE: Transcatheter arterial chemoembolization; HR: Hazard ratio; PFS: Progression free survival; TTUP: Time to untreatable or unTACEable progression; TTP: Time to progression; TTVI: Time to vascular invasion; TTEHS: Time to extrahepatic spread; TTSP: Time to stage progression.

Citation: Kudo M. Targeted and immune therapies for hepatocellular carcinoma: Predictions for 2019 and beyond. World J Gastroenterol 2019; 25(7): 789-807
URL: https://www.wjgnet.com/1007-9327/full/v25/i7/789.htm
DOI: https://dx.doi.org/10.3748/wjg.v25.i7.789