Increased circulating circular RNA_103516 is a novel biomarker for inflammatory bowel disease in adult patients

doi:10.3748/wjg.v25.i41.6273

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 7, 2019; 25(41): 6273-6288
Published online Nov 7, 2019. doi: 10.3748/wjg.v25.i41.6273

Table 3 Laboratory measures and disease activity scores of inflammatory bowel disease patients and control groups

Parameter	CD (n = 90)	UC (n = 90)	HCs (n = 80)	PCs (n = 35)
CRP (mg/L)	79.95 (18.47-121.22)	58.10 (16.43-123.67)	3.49 (3.30-6.09)	5.73 (3.84-7.94)
ESR (mm/H)	38.50 (17.75-67.00)	30.00 (15.00-58.00)	12.02 (4.87-14.25)	17.32 (3.87-26.85)
TNF-α (pg/mL)	6.83 (3.89-12.26)	6.70 (3.45-9.45)	--
INF-γ (pg/mL)	9.29 (5.77-12.35)	6.70 (4.4-10.65)	--
IL-10 (pg/mL)	10.99 (6.21-19.27)	11.3 (6.66-25.08)	--
CDAI score	270.15 (170.60-376.58)	--	--
Mayo score	--	5.00 (3.00-10.00)	--

The data are presented as medians (1/4-3/4 quarters). CD: Crohn’s disease; UC: Ulcerative colitis; HCs: Healthy controls; PCs: Patient controls; CRP: C reactive protein; ESR: Erythrocyte sedimentation rate; TNF-α: Tumor necrosis factor α; INF-γ: Interferon γ; IL-10: Interleukin-10; CDAI: Crohn’s disease activity index.

Citation: Ye YL, Yin J, Hu T, Zhang LP, Wu LY, Pang Z. Increased circulating circular RNA_103516 is a novel biomarker for inflammatory bowel disease in adult patients. World J Gastroenterol 2019; 25(41): 6273-6288
URL: https://www.wjgnet.com/1007-9327/full/v25/i41/6273.htm
DOI: https://dx.doi.org/10.3748/wjg.v25.i41.6273