Apparent diffusion coefficient-based histogram analysis differentiates histological subtypes of periampullary adenocarcinoma

Figure 6 Corresponding volumetric histograms of intestinal-type periampullary adenocarcinoma and pancreatobiliary-type periampullary adenocarcinoma. A: Corresponding volumetric histogram (b₈₀₀) shows the overlap distribution of ADC values of IPAC and PPAC. For the PPAC, the mean, 50th percentile, 75th percentile, and ADC_max were 1.35, 1.38, 1.55, and 2.14 × 10⁻³ mm²/s, respectively. For the IPAC, the mean, 50th percentile, 75th percentile, and ADC_max were 1.52, 1.53, 1.63, and 2.26 × 10⁻³ mm²/s, respectively; B: Corresponding volumetric histogram (b₁₀₀₀) shows a higher ADC distribution range in the IPAC. For the PPAC, the mean, 50th percentile, 75th percentile, and ADC_max were 0.96, 0.98, 1.14, and 1.80 ×10⁻³ mm²/s, respectively. For the IPAC, the mean, 50th percentile, 75th percentile, and ADC_max were 1.49, 1.47, 1.58, and 2.10 ×10⁻³ mm²/s, respectively. IPAC: Intestinal-type periampullary adenocarcinoma; PPAC: Pancreatobiliary-type periampullary adenocarcinoma; ADC: Apparent diffusion coefficient.