lncRNA-SNHG15 accelerates the development of hepatocellular carcinoma by targeting miR-490-3p/ histone deacetylase 2 axis

Figure 1 The dysregulation of lncRNA-SNHG15 in hepatocellular carcinoma. A: SNHG15 expression in 33 randomly selected hepatocellular carcinoma tissues and normal tissues; B: SNHG15 expression in HuH-1, HuH-7 and L-O2 cell lines; C: lncRNA-SNHG15 expression in HuH-1 and L-O2 cells containing SNHG15 siRNA or vector; D: Cell proliferation in HuH-1 and L-O2 cells with SNHG15 siRNA or vector; E: Cell migration in HuH-1 cells with SNHG15 siRNA or vector; F: Cell invasion in HuH-1 cells with SNHG15 siRNA or vector. Untreated cells were used as control (NC). ^aP < 0.05, ^bP < 0.01. SNHG15: Small nucleolar RNA host gene 15; HuH-1: Hepatocellular carcinoma cell line; HuH-7: Hepatocellular carcinoma cell line; L-O2: Normal human liver cell lin3; siRNA: Small interfering RNA.