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©The Author(s) 2019.
World J Gastroenterol. Sep 28, 2019; 25(36): 5515-5529
Published online Sep 28, 2019. doi: 10.3748/wjg.v25.i36.5515
Published online Sep 28, 2019. doi: 10.3748/wjg.v25.i36.5515
Table 3 Performance of protein induced by vitamin K absence or antagonist II, alpha-fetoprotein, and the ratio of gamma-glutamyltransferase and aspartate aminotransferase in hepatitis B virus DNA+ and hepatitis B virus DNA- hepatocellular carcinoma patients
| HBV DNA+ HCC | HBV DNA- HCC | |||||||||
| Cut-off | SEN (%) | SPE (%) | PPV (%) | NPV (%) | Cut-off | SEN (%) | SPE (%) | PPV (%) | NPV (%) | |
| PIVKA-II (mAu/mL) | 84.44 | 92.00 | 92.60 | 80.92 | 97.14 | 154.92 | 72.70 | 91.10 | 87.68 | 79.30 |
| AFP (ng/mL) | 497.70 | 58.00 | 88.80 | 63.85 | 86.11 | 146.15 | 58.00 | 97.00 | 94.40 | 72.61 |
| γ-GT/AST | 0.640 | 88.60 | 60.50 | 43.34 | 93.96 | 0.830 | 85.20 | 52.50 | 60.98 | 80.28 |
| PIVKA-II + AFP | NA | 89.80 | 92.20 | 79.70 | 96.36 | NA | 80.70 | 87.10 | 84.50 | 83.82 |
| PIVKA-II + γ-GT/AST | NA | 89.80 | 92.60 | 80.54 | 96.38 | NA | 79.50 | 78.20 | 76.06 | 81.41 |
| AFP + γ-GT/AST | NA | 70.50 | 89.10 | 68.81 | 89.85 | NA | 75.00 | 78.20 | 74.98 | 78.21 |
| PIVKA-II + AFP + γ-GT/AST | NA | 90.90 | 92.20 | 79.90 | 96.74 | NA | 79.50 | 86.10 | 83.29 | 82.82 |
- Citation: Wang Q, Chen Q, Zhang X, Lu XL, Du Q, Zhu T, Zhang GY, Wang DS, Fan QM. Diagnostic value of gamma-glutamyltransferase/aspartate aminotransferase ratio, protein induced by vitamin K absence or antagonist II, and alpha-fetoprotein in hepatitis B virus-related hepatocellular carcinoma. World J Gastroenterol 2019; 25(36): 5515-5529
- URL: https://www.wjgnet.com/1007-9327/full/v25/i36/5515.htm
- DOI: https://dx.doi.org/10.3748/wjg.v25.i36.5515