Feasibility of endoscopic treatment and predictors of lymph node metastasis in early gastric cancer

Table 1 Lymph node metastasis risk according to clinical parameters

	Total (n = 1262), n (%)	LNM negative (n = 1080), n (%)	LNM positive (n = 182), n (%)	Univariate OR (95%CI)	P-value
Age (yr)					0.090
≤ 60	628 (49.8)	548 (50.7)	80 (44.0)	1
> 60	634 (50.2)	532 (49.3)	102 (56.0)	1.313 (0.960, 1.800)
Sex					0.239
Male	899 (71.2)	776 (71.9)	123 (67.6)	1
Female	363 (28.8)	304 (28.1)	59 (32.4)	0.817 (0.580, 1.150)
Hypertension					0.554
Absence	958 (75.9)	823 (76.2)	135 (74.2)	1
Presence	304 (24.1)	257 (23.8)	47 (25.8)	1.115 (0.78, 1.60)
Heart disease					0.449
Absence	1146 (90.8)	978 (90.4)	168 (92.3)	1
Presence	116 (9.2)	102 (9.6)	14 (7.7)	0.799 (0.446, 1.430)
Diabetes mellitus					0.933
Absence	1142 (90.5)	977 (90.5)	165 (90.7)	1
Presence	120 (9.5)	103 (9.5)	17 (9.3)	0.977 (0.570, 1.675)
BMI					0.086
≤ 28	1134 (89.9)	964 (89.3)	170 (93.4)	1
> 28	128 (10.1)	116 (10.7)	12 (6.6)	0.587 (0.317, 1.086)
Drinking					0.104
Absence	827 (65.6)	698 (64.7)	129 (70.9)	1
Presence	434 (34.4)	381 (35.3)	53 (29.1)	0.753 (0.534, 1.061)
Smoking					0.138
Absence	692 (54.8)	583 (54.0)	109 (59.9)	1
Presence	570 (45.2)	497 (46.0)	73 (40.1)	0.786 (0.571, 1.082)
Family history					0.872
Absence	1011 (80.1)	866 (80.2)	145 (79.7)	1
Presence	251 (19.9)	214 (19.8)	37 (20.3)	1.033 (0.699, 1.526)
H. pylori infection					0.225
Negative	634 (50.2)	535 (49.5)	99 (54.4)	1
Positive	628 (49.8)	545 (50.5)	83(45.6)	0.823 (0.601, 1.128)
CEA					0.007
Negative	960 (76.1)	836 (77.4)	124 (68.1)	1
Positive	302 (23.9)	244 (22.6)	58 (31.9)	1.603 (1.137, 2.258)

LNM: Lymph node metastasis; OR: Odds ratio; CI: Confidence interval; BMI: Body mass index; H. pylori: Helicobacter pylori; CEA: Carcinoembryonic antigen.