MicroRNA-194 inactivates hepatic stellate cells and alleviates liver fibrosis by inhibiting AKT2

Figure 3 MiR-194 inhibits the proliferation of hepatic stellate cells. A: LX2 cells were treated with OV-miR-194/si-miR-194±TGF-β1. The CCK8 assay showed the proliferation of LX2 cells; B: The cell cycle was analyzed by flow cytometry; C: The mRNA expression of cyclin D1 analyzed by qPCR; D: The protein expression of cyclin D1 analyzed by Western blot. ^aP < 0.05 vs the con group; ^bP < 0.05 vs the TGF-β1 + OV-miR-NC group; ^cP < 0.05 vs the TGF-β1 + si-NC group.