Eosinophils in the gastrointestinal tract and their role in the pathogenesis of major colorectal disorders

Table 2 Cell surface markers expressed by eosinophils

Group of surface markers	Markers identified for eosinophils	Ref.
Cytokine and growth factor receptors	IL-2R, IL-3R, IL-4R, IL-5R, IL-9R, IL-10R, IL-13R, IL-17R, IL-23R, IL-27-R, IL-31R, IL-33R (ST2), TSLPR, GM-CSFR, KIT, IFNγR, TGFβR	[5,43-45]
Chemokine and chemoattractant receptors	CCR1, CCR3, CCR4, CCR5, CCR6, CCR8, CCR9, CXCR2, CXCR3, CXCR4, FPR1, FPR2, C3aR, C5aR	[5,43,44,46]
Lipid mediator receptors	Platelet-activating factor receptor, DP1 prostaglandin receptor, DP2 prostaglandin receptor (CRTH2), EP4 prostaglandin receptor, E2 prostaglandin receptor, Leukotriene B4 receptor, Lysophosphatidylserine receptor P2Y10, S1P receptors	[5,43,44,47]
Fc receptors	FcαR, FcγRII, FcγRIII, FcεRI, FcεRII	[5,43,44]
Adhesion molecule receptors	Integrin αLβ2 (LFA1), Integrin αMβ2 (CR3), Integrin αXβ2 (CR4), Integrin α4β1 (VLA4), Integrin α6β1, Integrin αDβ2, Integrin α4β7 (LPAM), cell surface adhesion receptor CD44, CD62L (L-selectin), PSGL1 (P-selectin lipoprotein ligand), CD34, CD244 (2B4)	[5,43,44,48,49]
Pattern recognition receptors	TLR1, TLR2, TLR3, TLR4, TLR5, TLR6, TLR7, TLR9, TLR10, NOD1, NOD2, RIG-1, RAGE	[5,43,44]
Other receptors and surface markers	PIRB, SIGLECs, SIRPα (shown for mice), LAIR1, Cannabinoid receptor CB2, Kinin B1 and B2 receptors, Histamine receptors, PAR1 or PAR2, CD80 or CD86, CD48, CD300 receptors (a and f), MHC class II	[5,43,44,50-53]