Ursodeoxycholic acid ameliorates hepatic lipid metabolism in LO2 cells by regulating the AKT/mTOR/SREBP-1 signaling pathway

Figure 4 Effect of ursodeoxycholic acid on oleic acid-induced activation of the AKT/mTOR signaling pathway. A: Activation of AKT and mTOR detected by Western blot assay. B: Relative quantitative analysis of phosphorylated AKT and mTOR in LO2 cells. Data are shown as the mean ± SE. ^aP < 0.05, ^bP < 0.01 vs ctrl group; ^cP < 0.01 vs model group. Ctrl: Control; UDCA: Ursodeoxycholic acid.