Elderly patients had more severe postoperative complications after pancreatic resection: A retrospective analysis of 727 patients

Table 1 Demographic, comorbidity, operation type, and pathology data in patients grouped according to age

Variable	< 65 yr, n = 454	≥ 65 yr, n = 273	Total, n = 727	P value
Sex
Male	202	159	361
Female	252	114	366
Male:female ratio	0.8	1.4	1.0	0.0003
Mean BMI in kg/m2	23.1	23.4	23.2	0.351
Smoking				0.129
Never	323	180	503
Ever	130	93	223
Mean smoking amount. in packs/yr	50	53	51	0.127
Mean smoking time in yr	22.1	26.1	23.7	0.101
Alcohol				0.017
Never	367	200	567
Ever	87	73	160
Mean preoperative TBIL in μmol/L	31.4	42.8	36.3	0.134
Preoperative serum albumin in g/L	39.7	37.8	38.9	0.111
ASA category III + IV	89	77	166	0.007
Preoperative biliary drainage	51	49	100	0.011
Comorbidity
Patients with any comorbidity	147	171	318	< 0.001
Diabetes	89	73	162	0.025
Coronary artery disease	18	57	75	< 0.001
Hypertension	77	63	140	0.043
COPD	11	12	23	0.141
HBV	26	9	35	0.138
HCV	11	4	15	0.379
Previous history of cancer	3	6	9	0.070
Previous abdominal surgery	61	37	98	0.964
Family history of cancer	49	50	99	0.004
Operation type
Pancreaticoduodenectomy	232	153	385	0.196
Distal pancreatectomy	169	112	281	0.308
Middle-segment pancreatectomy	43	8	51	0.0008
Pathology data
Pancreatic duct adenocarcinoma	94	101	195	< 0.001
Others1	360	172	532

¹Distal bile duct adenocarcinoma, ampulla adenocarcinoma, gall bladder adenocarcinoma, duodenal adenocarcinoma, intraductal papillary mucinous neoplasm, neuroendocrine neoplasm, pancreatic metastasis, solid pseudopapillary tumor, benign neoplasm, pancreatitis. ASA: American Society of Anesthesiologists; BMI: Body mass index; COPD: Chronic obstructive pulmonary disease; HBV: Hepatitis B virus; HCV: Hepatitis C virus; TBIL: Total bilirubin.