Incidence of hepatocellular carcinoma in patients with chronic liver disease due to hepatitis B or C and coinfected with the human immunodeficiency virus: A retrospective cohort study

Table 2 Characteristics of patients with hepatocellular carcinoma¹

Characteristics	HIV+ (n = 10)	HIV- (n= 26)	P value
Age, yr	42.1 ± 8.3	53.7 ± 10.6	0.004
Male gender	8 (80.0)	18 (69.2)	0.689
Caucasian	9 (90.0)	24 (92.3)	> 0.999
Diabetes or glucose intolerance	2 (20.0)	10 (41.7)	0.432
	n = 9	n = 22
Alcohol	7 (77.8)	10 (45.5)	0.132
	n = 10	n = 26
Hepatitis B	1 (10.0)	2 (7.7)	> 0.99
Hepatitis C	9 (90.0)	24 (92.3)	> 0.99
Child- Pugh	n = 8	n = 25
A	2 (25.0)	11 (44.0)	0.735
B	5 (62.5)	11 (44.0)
C	1 (12.5)	3 (12.0)
	n = 7	n = 22
MELD	13.7 ± 5.1	10.9 ± 4.2	0.157
	n = 10	n = 26
Milan criteria2	3 (30.0)	14 (53.8)	0.157
	n = 10	n = 24
Alpha-fetoprotein, ng/mL	276 (23-18750)	20 (4-113)	0.038

Data presented as average ± SD or n (%). ¹All patients who developed hepatocellular carcinoma in this study had liver cirrhosis;

²Patients with hepatocellular carcinoma satisfying the following criteria: single lesion < 5 cm or up to three lesions < 3 cm, without vascular tumor invasion and/or distant metastasis. HIV: Human immunodeficiency virus; MELD: Model for End-Stage Liver Disease.