Ubiquitin-like modifier activating enzyme 2 promotes cell migration and invasion through Wnt/β-catenin signaling in gastric cancer

Figure 4 Ubiquitin-like modifier activating enzyme 2 facilitates cell cycle progression and regulates expression of cell cycle-related proteins. A: Cell cycle analysis by flow cytometry in BGC-823 and SGC-7901 cells. ^aP < 0.05 vs Control; ^bP < 0.05 vs EV; B: Expression of cyclinD1, P21, P27, CDK4, and Bcl-2. All experiments were performed in triplicate. CDK4: Cyclin-dependent kinase 4; EV: Empty vector; Uba2: Ubiquitin-like modifier activating enzyme 2.