CXC family of chemokines as prognostic or predictive biomarkers and possible drug targets in colorectal cancer

doi:10.3748/wjg.v24.i42.4738

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 14, 2018; 24(42): 4738-4749
Published online Nov 14, 2018. doi: 10.3748/wjg.v24.i42.4738

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Figure 1 CXCL and CXCR regulatory mechanisms. Figure 1 illustrates CXCL binding to the CXCR located at the cellular membrane, internalizing and transducing the signal into the nucleus. CXCR internalization is usually followed by degradation or recycling to the plasma membrane.

Citation: Heras SCDL, Martínez-Balibrea E. CXC family of chemokines as prognostic or predictive biomarkers and possible drug targets in colorectal cancer. World J Gastroenterol 2018; 24(42): 4738-4749
URL: https://www.wjgnet.com/1007-9327/full/v24/i42/4738.htm
DOI: https://dx.doi.org/10.3748/wjg.v24.i42.4738

Heras SCDL, Martínez-Balibrea E. CXC family of chemokines as prognostic or predictive biomarkers and possible drug targets in colorectal cancer. World J Gastroenterol 2018; 24(42): 4738-4749 [PMID: 30479461 DOI: 10.3748/wjg.v24.i42.4738]

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