Copyright
©The Author(s) 2018.
World J Gastroenterol. Oct 28, 2018; 24(40): 4596-4605
Published online Oct 28, 2018. doi: 10.3748/wjg.v24.i40.4596
Published online Oct 28, 2018. doi: 10.3748/wjg.v24.i40.4596
Adverse event | Number | Severe | Impact on treatment |
Abdominal discomfort | 39 (4.5) | - | 2 stopped prior to completion (10, 12 d) |
Dizziness | 11 (1.3) | 2 (0.2) | 4 stopped prior to completion (7, 10, 10, 12 d); 1 experienced dizziness after drinking alcohol and stopped prior to completion (10 d); 1 took 50% medicine |
Nausea (with/without vomiting) | 20 (2.3) | - | 1 took 75% medicine |
Fatigue | 11 (1.3) | 1 (0.1) | 1 stopped prior to completion (12 d); 1 changed to traditional Chinese medicine during therapy (7 d) |
Anorexia | 13 (1.5) | - | 1 took 80% medicine |
Skin rash/pruritus | 18 (2.1) | 3 (0.4) | 4 stopped prior to completion (4, 7, 10, 11 d); 2 changed to other regimens during therapy (2, 10 d); 1 took half of amoxicillin and all other drugs |
Fever | 2 (0.2) | 2 (0.2) | 2 stopped prior to completion (7, 9 d) |
Diarrhea | 9 (1.1) | 1 (0.1) | 1 stopped prior to completion (less than 7 d) |
Constipation | 3 (0.4) | - | - |
Flatulence | 2 (0.2) | - | - |
Muscle pain or spasm (shoulder/back) | 3 (0.4) | - | - |
Acid regurgitation | 1 (0.1) | - | - |
Abdominal pain | 4 (0.5) | 1 (0.1) | 2 stopped prior to completion (7,10 d) |
Weight loss | 3 (0.4) | - | - |
Bitter taste/dry throat | 2 (0.2) | - | 1 took 75% medicine |
Belching | 1 (0.1) | - | - |
Chest congestion | 1 (0.1) | - | - |
Heartburn | 1 (0.1) | - | - |
Total | 144 (16.8) | 10 (1.2) | 24 (2.8) |
- Citation: Zhang YW, Hu WL, Cai Y, Zheng WF, Du Q, Kim JJ, Kao JY, Dai N, Si JM. Outcomes of furazolidone- and amoxicillin-based quadruple therapy for Helicobacter pylori infection and predictors of failed eradication. World J Gastroenterol 2018; 24(40): 4596-4605
- URL: https://www.wjgnet.com/1007-9327/full/v24/i40/4596.htm
- DOI: https://dx.doi.org/10.3748/wjg.v24.i40.4596