Diet switch and omega-3 hydroxy-fatty acids display differential hepatoprotective effects in an obesity/nonalcoholic fatty liver disease model in mice

doi:10.3748/wjg.v24.i4.461

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 28, 2018; 24(4): 461-474
Published online Jan 28, 2018. doi: 10.3748/wjg.v24.i4.461

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Figure 7 NAS score. (A) Steatosis, (B) hepatocyte ballooning, (C) lobular and (D) portal inflammation. Bars represent the percentage of animals in the group at the given score. According to NAS, steatosis was graded 0-3, hepatocyte ballooning 0-2, lobular inflammation 0-3, and portal inflammation (0-2). Groups: CD (n = 6), HFD (n = 6), HFD + DS (n = 6), HFD + 18-HEPE (n = 6), HFD+17-HDHA (n = 6). ^aP < 0.05 vs CD, ^cP < 0.05 vs HFD by Fisher’s exact test.

Citation: Rodriguez-Echevarria R, Macias-Barragan J, Parra-Vargas M, Davila-Rodriguez JR, Amezcua-Galvez E, Armendariz-Borunda J. Diet switch and omega-3 hydroxy-fatty acids display differential hepatoprotective effects in an obesity/nonalcoholic fatty liver disease model in mice. World J Gastroenterol 2018; 24(4): 461-474
URL: https://www.wjgnet.com/1007-9327/full/v24/i4/461.htm
DOI: https://dx.doi.org/10.3748/wjg.v24.i4.461

Rodriguez-Echevarria R, Macias-Barragan J, Parra-Vargas M, Davila-Rodriguez JR, Amezcua-Galvez E, Armendariz-Borunda J. Diet switch and omega-3 hydroxy-fatty acids display differential hepatoprotective effects in an obesity/nonalcoholic fatty liver disease model in mice. World J Gastroenterol 2018; 24(4): 461-474 [PMID: 29398867 DOI: 10.3748/wjg.v24.i4.461]

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