Diet switch and omega-3 hydroxy-fatty acids display differential hepatoprotective effects in an obesity/nonalcoholic fatty liver disease model in mice

Figure 4 Hepatic proteins involved in lipid oxidation and synthesis. PPARα (A), CPT1A (B), ACOX1 (C), LXRα (D), SREBP1 in both precursor (E) and cleaved form (F). Every two bands from left to right are representative of each group. All data are mean ± SEM. Groups: CD (n = 6), HFD (n = 6), HFD + DS (n = 6), HFD + 18-HEPE (n = 6), HFD + 17-HDHA (n = 6). ^aP < 0.05 vs CD, ^cP < 0.05 vs HFD by Mann-Whitney U test. HFD: High-fat, fructose-enriched diet.