Sex-specific effects of Eugenia punicifolia extract on gastric ulcer healing in rats

Figure 10 Epidermal growth factor expression in the gastric mucosa of rats with acetic acid-induced gastric ulcers treated with oral administration of vehicle, lansoprazole, or hydroalcoholic extract from the leaves of Eugenia punicifolia for 14 d. Data represent relative expression of EGF normalized to the expression of housekeeping genes (actin). The results represent mean ± standard error of the mean for each group (n = 6). Statistical significance was determined using one-way ANOVA followed by Dunnett's test or Student’s t-test. ^aP < 0.01 vs vehicle in males; ^bP < 0.01 vs vehicle in ovariectomized females; ^cP < 0.05 for lansoprazole in males vs intact females; ^dP < 0.05 for lansoprazole in intact vs ovariectomized females. HEEP: Hydroalcoholic extract from the leaves of Eugenia punicifolia.