Temporal clinical, proteomic, histological and cellular immune responses of dextran sulfate sodium-induced acute colitis

Figure 6 Immune cell population in the spleen, mesenteric lymph nodes and colon of 3% dextran sulfate sodium animals. Tissue samples were collected from 3% DSS animals at different time points and analyzed through either immunohistochemistry or flow cytometry. The heatmap shows a possible movement of different immune cell types from the spleen and MLN into the gut progressively during the 8 d of disease. ^aP < 0.05 increased fold changes compared to control (day 0). ^bP < 0.05 decreased fold changes compared to control (day 0). MLN: Mesenteric lymph nodes; DSS: Dextran sulfate sodium.