Low expression of CDK5RAP3 and DDRGK1 indicates a poor prognosis in patients with gastric cancer

Table 2 Relationship between different CDK5RAP3 and DDRGK1 protein expression status in gastric cancer tissues and various clinicopathological variables

Variables	Total	C53 and DDRGK1 low expression	C53 and/or DDRGK1 high expression	χ2	P value
Gender
Male	107	59	48	5.077	0.024
Female	28	22	6
Age (yr)
> 60	91	55	36	0.022	0.881
≤ 60	44	26	18
Tumor size (cm)
> 5	53	32	21	0.005	0.943
≤ 5	82	49	33
Location of tumor
Lower 1/3	55	33	22	1.481	0.687
Middle 1/3	20	12	8
Upper 1/3	45	29	16
More than 1/3	15	7	8
Borrmann type
I + II Type	31	20	11	0.342	0.559
III + IV Type	104	61	43
Degree of differentiation
Well/moderate	57	31	26	1.296	0.255
Poor and not	78	50	28
Histological type
Papillary	57	33	25	4.415	0.220
Tubular	42	22	20
Mucinous	10	8	2
Signet-ring cell	25	18	7
Depth of invasion
T1 + T2	21	8	13	4.972	0.026
T3 + T4	114	73	41
Lymph node metastasis
Negative	20	8	12	3.913	0.048
Positive	115	73	42
TNM stage
I + II	44	20	24	5.754	0.016
III + IV	91	61	30
Distant metastasis
Negative	126	75	53	2.034	0.154
Positive	7	6	1