Prognostic significance of the fibrinogen-to-albumin ratio in gallbladder cancer patients

Table 4 Correlation between FAR and clinicopathological characteristics in gallbladder cancer patients n (%)

Characteristics	FAR		P value
	≤ 0.08(n = 71)	> 0.08(n = 83)
Age (yr)
≤ 60	32 (20.8)	24 (15.6)	0.045
> 60	39 (25.3)	59 (38.3)
Sex
Male	30 (19.5)	33 (21.4)	0.870
Female	41 (26.6)	50 (32.5)
Cholecystolithiasis
Absent	37 (24.0)	42 (27.3)	0.873
Present	34 (22.1)	41 (26.6)
Diabetes
Absent	56 (36.4)	60 (39.0)	0.357
Present	15 (9.7)	23 (14.9)
Jaundice
Absent	67 (43.5)	62 (40.3)	< 0.001
Present	4 (2.6)	21 (13.6)
Blood groups
A	22 (14.3)	21 (13.6)	0.148
B	28 (18.2)	28 (18.2)
AB	1 (0.6)	8 (5.2)
O	20 (13.0)	26 (16.9)
Pathological types
Adenosquamous carcinoma	0 (0)	3 (1.9)	0.173
Adenocarcinoma	71 (46.1)	79 (51.3)
Papillocarcinoma	0 (0)	1 (0.6)
Degree of differentiation
Poor	18 (11.7)	42 (27.3)	0.002
Moderate-well	53 (34.4)	41 (26.6)
Resection margin status
Negative	55 (35.7)	41 (26.6)	< 0.001
Positive	16 (10.4)	42 (27.3)
Maximum tumor diameter (cm)
≤ 2.45	37 (24.0)	31 (20.1)	0.075
> 2.45	34 (22.1)	52 (33.8)
T stage
Tis-T1a	8 (5.2)	2 (1.3)	< 0.001
T1b-T2b	24 (15.6)	5 (3.2)
T3	36 (23.4)	67 (43.5)
T4	3 (1.9)	9 (5.8)
N stage
N0	48 (31.2)	50 (32.5)	0.623
N1	19 (12.3)	28 (18.2)
N2	4 (2.6)	5 (3.2)
Distant metastasis
Absent	68 (44.2)	74 (48.1)	0.145
Present	3 (1.9)	9 (5.8)
TNM stage
0-Istage	14 (9.1)	2 (1.3)	< 0.001
IIA-IIB stage	14 (9.1)	2 (1.3)
IIIA-IIIB stage	35 (22.7)	57 (37.0)
IVA-IVB stage	8 (5.2)	22 (14.3)
CA199 (U/mL)
≤ 39	43 (27.9)	23 (14.9)	< 0.001
> 39	28 (18.2)	60 (39.0)
Fibrinogen concentration (g/L)
≤ 3.47g/L	59 (38.3)	16 (10.4)	< 0.001
> 3.47 g/L	12 (7.8)	67 (43.5)
Albumin levels (g/L)
≤ 40.5g/L	21 (13.6)	55 (35.7)	< 0.001
> 40.5 g/L	50 (32.5)	28 (18.2)