Impact of hyperglycemia on autoimmune pancreatitis and regulatory T-cells

Figure 2 Evaluation of autoimmune pancreatitis. A: Representative images of the histological scores of autoimmune pancreatitis. Arrows point at small inflammatory infiltrates embedded in healthy surrounding tissue; B: hyperglycemia (STZ) reduced the histological score slightly compared to normoglycemic controls (sham); little differences are observed in the pancreas to body weight ratio (C), lipase activity (D), and amylase activity (E). The number of animals evaluated was n = 19 (sham) and n = 17 (STZ) in Panel B and C and n = 19 (Sham) and n = 15 (STZ) in D and E. Scale bar = 50 μm. STZ: Streptozotocin-treated.