Liver intravoxel incoherent motion diffusion-weighted imaging for the assessment of hepatic steatosis and fibrosis in children

Table 4 Multivariate linear regression analysis for intravoxel incoherent motion parameters in all groups

	D (× 10-3 mm2/s)			D* (× 10-3 mm2/s)			f (%)			ADC (× 10-3 mm2/s)
	β	SE	P value	β	SE	P value	β	SE	P value	β	SE	P value
AST (IU/L)	-2.222	1.337	0.100	-0.063	0.161	0.697	-0.485	0.408	0.238	-1.343	1.227	0.277
ALT (IU/L)	0.718	0.673	0.289	0.013	0.081	0.877	0.116	0.206	0.574	0.419	0.618	0.499
PDFF (%)	-1.228	2.622	0.640	0.381	0.315	0.230	3.194	0.801	< 0.001a	-3.663	2.407	0.131
T2* (millisecond)	-11.189	4.697	0.019a	1.316	0.565	0.022a	-0.847	1.435	0.557	-8.473	4.313	0.052
MRE (kPa) (n = 103)	-37.042	26.853	0.171	-7.031	3.231	0.032a	-11.667	8.206	0.158	-29.679	24.658	0.232

^aP < 0.05; IVIM: Intravoxel incoherent motion; ADC: Apparent diffusion coefficient; β: Coefficient; SE: Standard error of the estimated coefficient; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; PDFF: MR proton density fat fraction; MRE: MR elastography.