MicroRNAs in the prognosis and therapy of colorectal cancer: From bench to bedside

Table 4 A list of representative miRNAs isolated from exosomes in biological samples from colorectal cancer patients or cell lines that are of prognostic value

miRNA	Method of detection	Type of samples	Tumor stage	Ref.
miR-17-92a	miRNA microarray	Tumor specimens	IV	[78]
miR-19a	miRNA microarray	Tumor specimens	IV	[78]
let-7a	qRT-PCR	Serum	I, II, IIIa, IIIb, IV	[214]
miR-21	qRT-PCR and miRNA microarray	Serum; plasma	I, II, IIIa, IIIb, IV	[214]
miR-23a	qRT-PCR	Serum	I, II, IIIa, IIIb, IV	[214]
miR-150	qRT-PCR	Serum	I, II, IIIa, IIIb, IV	[214]
miR-203	qRT-PCR	Serum	I, II, III, IV	[215]
miR-223	qRT-PCR	Serum	I, II, IIIa, IIIb, IV	[214]
miR-1246	qRT-PCR	Serum	I, II, IIIa, IIIb, IV	[214]
miR-1229	qRT-PCR	Serum	I, II, IIIa, IIIb, IV	[214]
miR-548c-5p	miRNA microarray and qRT-PCR	Serum (downregulated)	I, II, IIIa, IIIb, IV	[216]
miR-638	miRNA microarray and qRT-PCR	Serum (downregulated)	I, II, IIIa, IIIb, IV	[216]
miR-5787	miRNA microarray and qRT-PCR	Serum (downregulated)	I, II, IIIa, IIIb, IV	[216]
miR-8075	miRNA microarray and qRT-PCR	Serum (downregulated)	I, II, IIIa, IIIb, IV	[216]
miR-6869-5p	miRNA microarray and qRT-PCR	Serum (downregulated)	I, II, IIIa, IIIb, IV	[216]
miR-486-5p	miRNA microarray and qRT-PCR	Serum (upregulated)	I, II, IIIa, IIIb, IV	[216]
miR-3180-5p	miRNA microarray and qRT-PCR	Serum (upregulated)	I, II, IIIa, IIIb, IV	[216]
miR-96-5p and miR-149	qRT-PCR	Plasma	III	[217]
miR-100	qRT-PCR	Cell lines (DKO-1, Dks-8, DLD-1)		[218]
miR-192	qRT-PCR	Cell lines (HCT-15, SW480, WiDr)		[219]
miR-210	qRT-PCR	Cell line (HCT-8)		[220]
miR-221	qRT-PCR	Cell lines (HCT-15, SW480, WiDr)		[219]
miR-379	qRT-PCR	Cell lines (HCT-116, HT-29)		[221]