INT-767 improves histopathological features in a diet-induced ob/ob mouse model of biopsy-confirmed non-alcoholic steatohepatitis

doi:10.3748/wjg.v24.i2.195

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Jan 14, 2018 (publication date) through May 10, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 14, 2018; 24(2): 195-210
Published online Jan 14, 2018. doi: 10.3748/wjg.v24.i2.195

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Figure 8 INT-767 and obeticholic acid (OCA) treatment for 16 wk improves liver histopathology in ob/ob-NASH mice with biopsy-confirmed liver pathology. Composite NAS and fibrosis stage before and after treatment intervention. ^aP < 0.05, ^bP < 0.001 (χ² test, vs vehicle controls), NASH: Non-alcoholic steatohepatitis.

Citation: Roth JD, Feigh M, Veidal SS, Fensholdt LK, Rigbolt KT, Hansen HH, Chen LC, Petitjean M, Friley W, Vrang N, Jelsing J, Young M. INT-767 improves histopathological features in a diet-induced ob/ob mouse model of biopsy-confirmed non-alcoholic steatohepatitis. World J Gastroenterol 2018; 24(2): 195-210
URL: https://www.wjgnet.com/1007-9327/full/v24/i2/195.htm
DOI: https://dx.doi.org/10.3748/wjg.v24.i2.195