Short- and long-term outcomes following laparoscopic vs open surgery for pathological T4 colorectal cancer: 10 years of experience in a single center

Table 7 Studies about laparoscopic surgery for pathological T4 colorectal cancer

Ref.	n (LAP:OPEN)	Study period	Study design	Country	Single/Multi center	Conversion rate	Location	Complication rate (LAP:OPEN)	Tumor stage	Combined resection (LAP:OPEN)	RI rate(LAP:OPEN)	5 years DFS (LAP:OPEN)	5 years OS (LAP:OPEN)
Park et al[22], 2016	93:18	2000-2010	RS	South Korea	Single	5.6%	Colon	14.1%:31.5%	-	9.9%:32.5%	5.5%:4.5%	81.8%:73.9%	95.3%:86.5%
							rectum
Shukla et al[20], 2015	61:22	2003-2011	RS	United States	Single	21%	Colon	28%:36%	II:35	23%:41%	0%:4%	75%:65%	82%:81%
									III:48			(3 yr)	(3 yr)
Kang et al[29], 2016	52:57	2003-2013	RS	South Korea	Single	7.7%	Colon	13.5%:36.8%	II:41	13.5%:36.8%	-	53.6%:62.6%	60.7%:61.9%
									III:68
de’Angelis et al[18], 2016	106:106	2005-2014	RPSM	France	Multi	12.2%	Colon	29.1%:35.3%	II:85	14.2%:18.9%	5.7%:6.6%	58.6%:59.9%	57.6%:50.2%
				Switzerland					III:127
de’Angelis et al[17], 2016	52:52	2005-2015	RPSM	France	Multi	21.2%	Rectum	30.8%:48.1%	II:42	26.9%:30.8%	19.2%:17.3%	66.7%:64.1%	55.4%:53.3%
				Switzerland					III:33
				Spain					IV:29
Chan et al[30], 2016	93:59	2008-2014	RS	Singapore	Single	8.6%	Colon	-	-	0%:3.4%	0%:0.7%	-	75%:80%
Leon et al[27], 2017	68:79	2008-2015	RS	Italy	Single	19%	Colon	7.4%:16.5%	II:69	-	11.8%:11.5%	40.3%:38.9%	44.6%:39.4%
									III:78
Ahmad et al[25], 2015	455:406	2011-2012	RS	Canada	ACSNS	24.7%	Colon	-	-	-	26.2%:24.3%	-	-
					QIP

LAP: Laparoscopy; RS: Retrospective study; RPSM: Retrospective propensity score matching; ACSNS: American College of Surgeons National Surgical Quality Improvement Program; OS: Overall survival; DFS: Disease-free survival.