Retrospective Study
Copyright ©The Author(s) 2018.
World J Gastroenterol. Jan 7, 2018; 24(1): 76-86
Published online Jan 7, 2018. doi: 10.3748/wjg.v24.i1.76
Table 6 Univariate and multivariate analyses of 211 pathological T4 colorectal cancer patients for disease-free survival
Univariate analysis
Multivariate analysis
VariableHR (95%CI)P valueHR (95%CI)P value
Age1.621 (1.010-2.601)0.0451.892 (1.111-3.223)0.419
Gender1.328 (0.824-2.141)0.243
Surgical method (LAP and OPEN)1.503 (0.933-2.422)0.094
Tumor location
Mid/upper rectumReference group-
Left colon1.010 (0.601-10697)0.969
Right colon0.818 (0.411-1.629)0.568
Comorbidities1.787 (1.058-3.019)0.0302.261 (1.235-4.139)0.080
pT4a/b0.818 (0.618-1.725)0.0131.214 (0.784-1.974)0.001
N stage
N0Reference group-
N11.134 (0.594-2.167)0.703
N21.553 (0.861-2.801)0.144
TNM stage
IIB + IICReference group-Reference group-
IIIB1.034 (0.471-2.269)0.9330.884 (0.393-1.989)0.765
IIIC2.284 (1.202-4.337)0.0121.831 (0.935-3.584)0.018
Lymph node status0.710 (0.411-1.229)0.221
No. of lymph nodes resected0.661 (0.411-1.061)0.087
Histological subtype0.456 (0.243-0.854)0.0140.469 (0.225-0.974)0.042
Differentiation0.439 (0.266-0.725)0.0010.662 (0.374-1.170)0.156
CA19-92.458 (1.526-3.960)0.0003.372 (1.968-5.778)0.000
CEA1.268 (0.790-2.036)0.3260.608 (0.356-1.038)0.072
Chemotherapy2.157 (1.323-3.514)0.0023.817 (2.194-6.639)0.000