Optimizing hepatitis C virus treatment through pharmacist interventions: Identification and management of drug-drug interactions

doi:10.3748/wjg.v23.i9.1618

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Mar 7, 2017; 23(9): 1618-1626
Published online Mar 7, 2017. doi: 10.3748/wjg.v23.i9.1618

Table 2 Drug-drug interactions identified from baseline medication list

Regimen	n = 664	Total number of meds	Total number of interactions, n (%)	Average number of meds per patient	Average number of interactions per patient	Contra-indications
LDV/SOF	369	2996	472 (15.8)	8.12	1.28	7
OBV/PTV/r + DSV	48	312	119 (38.1)	6.50	2.48	4
SIM/SOF	114	1002	169 (16.8)	8.79	1.48	19
SOF/RBV	133	964	21 (2.2)	7.25	0.16	1

LDV: Ledipasvir; SOF: Sofosbuvir; OBV: Ombitasvir; PTV: Paritaprevir; DSV: Dasabuvir; SIM: Simeprevir; RBV: Ribavirin.

Citation: Langness JA, Nguyen M, Wieland A, Everson GT, Kiser JJ. Optimizing hepatitis C virus treatment through pharmacist interventions: Identification and management of drug-drug interactions. World J Gastroenterol 2017; 23(9): 1618-1626
URL: https://www.wjgnet.com/1007-9327/full/v23/i9/1618.htm
DOI: https://dx.doi.org/10.3748/wjg.v23.i9.1618