Autoantibody profiles in autoimmune hepatitis and chronic hepatitis C identifies similarities in patients with severe disease

Table 6 Autoantibody positive chronic hepatitis C and autoimmune hepatitis, comparison of different parameters (mean ± SD)

Parameters	Autoantibody positive CHC (n = 18)	Autoantibody positive AIH (n = 20)	P value
IgG (mg/dL)	2109 ± 249	2053 ± 710.5	0.42 NS
IgM (mg/dL)	190 ± 26.8	227 ± 63.1	0.0271
AP (U/L)	428 ± 37.9	373 ± 166.1	0.33 NS
AST (U/L)	52 ± 8.42	57 ± 18.64	0.42 NS
ALT (U/L)	36 ± 5.5	37 ± 15.6	0.81 NS
TSB (mg/dL)	1.5 ± 4.1	4.0 ± 7.0	0.00332
Albumin (g/L)	3.8 ± 0.78	3.3 ± 0.69	0.12 NS

^1,2Indicate significant difference on the 0.05 and the 0.01 level respectively, NS indicates non-significance. Statistically significant differences were determined using analysis of variance followed by Duncan’s test. CHC: Chronic hepatitis C; AIH: Autoimmune hepatitis; AP: Alkaline phosphatase; AST: Aspartate transaminase; TSB: Total serum bilirubin; ALT: Alanine transaminase.