Structural shift of gut microbiota during chemo-preventive effects of epigallocatechin gallate on colorectal carcinogenesis in mice

Figure 3 Chemo-preventive effect of epigallocatechin gallate on colorectal carcinogenesis in azoxymethane/dextran sulfate sodium-treated mice. A and B: Representative hematoxylin and eosin stained histological sections of the control, model, and EG groups. A: × 10; B:× 40; C: Number of colon tumors and tumor load were reduced very significantly in the epigallocatechin gallate (EGCG) group compared to the model group (P < 0.01 and P < 0.001, respectively); D: Representative macroscopic morphology of colon tumors in the model and EG groups. Arrows indicate the azoxymethane/dextran sodium sulfate-induced tumors.