Structural shift of gut microbiota during chemo-preventive effects of epigallocatechin gallate on colorectal carcinogenesis in mice

Figure 1 Experimental protocol. Experimental FVB /N mice were divided into three groups, i.e., control group, model group, and epigallocatechin gallate treatment group. Animals in the model and EG groups initially received a single intraperitoneal injection of azoxymethane (AOM: 10 mg/kg). After the AOM administration, mice in the model and EG groups received 2.5% dextran sodium sulfate (DSS) in drinking water for 3 consecutive days. Mice in the EG group also received oral 1% EGCG 20 mg/kg per day for 13 wk. AOM: Azoxymethane; EGCG: Epigallocatechin gallate.