Structural shift of gut microbiota during chemo-preventive effects of epigallocatechin gallate on colorectal carcinogenesis in mice

Table 2 Effects of epigallocatechin gallate on azoxymethane-induced aberrant crypt foci in FVB mice (8^th week): distribution of aberrant crypt foci along the large bowel and comparison of aberrant crypt foci in different parts

Group	Treatment	n	Length (cm)	Rate (%)	Number of ACF
					Proximal	Distal	Entire
1	Control	5	9.73 ± 0.76	/	/	/	/
2	AOM/DSS (MO)	8	8.27 ± 0.37	100	1.13 ± 1.36	12.50 ± 3.67	13.13 ± 3.02
3	AOM/DSS + 1% EGCG	8	8.68 ± 0.471	75	0.63 ± 0.87	4.75 ± 3.702	5.38 ± 4.242

¹Different from group 2 (P < 0.05);

²Significantly different from group 2 (P < 0.01). AOM: Azoxymethane; DSS: Dextran sodium sulfate; EGCG: Epigallocatechin gallate; ACF: Aberrant crypt foci.