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Copyright ©The Author(s) 2017.
World J Gastroenterol. Nov 21, 2017; 23(43): 7657-7665
Published online Nov 21, 2017. doi: 10.3748/wjg.v23.i43.7657
Figure 1
Figure 1 Endoplasmic reticulum stress and unfolded protein response signaling pathways. ER: Endoplasmic reticulum; BIP: Binding immunoglobulin protein; PERK: Protein kinase RNA-like ER kinase; eIF2α: Eukaryotic translational initiation factor 2α; ATF4: Activating transcription factor 4; IRE1: Inositol-requiring protein 1; XBP1: X-box binding protein 1; ATF6: Activating transcription factor 6; S1P: Site 1 protease; S2P: Site 2 protease; UPR: Unfolded protein response; ERAD: ER associated degradation; CHOP: C/EBP homologous protein; P: Phosphate.