Copyright
©The Author(s) 2017.
World J Gastroenterol. Oct 21, 2017; 23(39): 7139-7149
Published online Oct 21, 2017. doi: 10.3748/wjg.v23.i39.7139
Published online Oct 21, 2017. doi: 10.3748/wjg.v23.i39.7139
Table 1 Enteropathic spondyloarthritis patient features
| ES-AN, n = 52 | ES-AN/Ada, n = 30 | |
| Crohn’s disease:Ulcerative colitis | 31 (60):21 (40) | 19 (63):11 (37) |
| Males:Females | 22 (42):30 (58) | 17 (57):13 (43) |
| Age in years | 47.2 ± 14.2 | 46.2 ± 14.4 |
| Disease duration of IBD in years | 11.3 ± 10.1 | 8.8 ± 7.9 |
| Smokers:Ex-smokers | 9 (17):20 (38) | |
| HLA-B27 positivity | 5 (10) | 4 (13) |
| Prior surgical intervention for IBD | 13 (25) | 5 (17) |
| Previous extra-intestinal disease | 6 (11) | 5 (17) |
| Eritema nodosum | 2 | 1 |
| Uveitis | 3 | 3 |
| Pioderma gangrenosum | 1 | 1 |
| Crohn’s disease activity by CDAI | ||
| Inactive | 14 (45) | 7 (37) |
| Moderate | 10 (32) | 8 (42) |
| Moderate-to-Severe | 7 (23) | 4 (21) |
| Ulcerative colitis activity by partial Mayo | ||
| Mild | 18 (86) | 8 (73) |
| Moderate | 3 (14) | 3 (27) |
| Severe | 0 | 0 |
| Current medication at baseline | ||
| Non-steroids anti-inflammatory drugs | 3 | 0 |
| Sulfasalazine | 3 | 2 |
| Mesalazine | 25 | 12 |
| Cyclosporine | 1 | 1 |
| Azathioprine | 9 | 5 |
| Oral steroids | 12 | 7 |
| Topical steroids | 3 | 2 |
| Metotrexate | 2 | 1 |
| Infliximab | 6 | 4 |
| Adalimumab | 2 | 0 |
| Spondyloarthritis features | ||
| Ankylosing spondylitis according to Modified New York Criteria | 16 (31) | 10 (33) |
| Non-radiographic Axial-Spondyloarthritis by ASAS Criteria | 13 (25) | 10 (33) |
| Peripheral- Spondyloarthritis | 23 (44) | 10 (33) |
| Type of axial involvement | n = 29 | n = 20 |
| Syndesmophytosis | 8 (28) | 6 (30) |
| Bamboo spine | 2 (7) | 2 (10) |
| Sacroiliitis by MRI and/or X-ray | 29 (100) | 20 (100) |
| Type of articular involvement in Crohn’s disease | n = 31 | n = 19 |
| Axial | 16 (52) | 11 (58) |
| Axial and peripheral | 4 | 3 |
| Peripheral only | 15 (48) | 8 (42) |
| Enthesitis | 9 (29) | 5 (26) |
| Type of articular involvement in ulcerative colitis | n = 21 | n = 11 |
| Axial | 13 (62) | 9 (82) |
| Axial and peripheral | 9 | 5 |
| Peripheral only | 8 (38) | 2 (18) |
| Enthesitis | 4 (19) | 2 (18) |
- Citation: Luchetti MM, Benfaremo D, Ciccia F, Bolognini L, Ciferri M, Farinelli A, Rossini M, Mosca P, Triolo G, Gabrielli A. Adalimumab efficacy in enteropathic spondyloarthritis: A 12-mo observational multidisciplinary study. World J Gastroenterol 2017; 23(39): 7139-7149
- URL: https://www.wjgnet.com/1007-9327/full/v23/i39/7139.htm
- DOI: https://dx.doi.org/10.3748/wjg.v23.i39.7139