Serum angiotensin-converting enzyme level for evaluating significant fibrosis in chronic hepatitis B

Figure 2 Serum levels of angiotensin-converting enzyme and fibrotic markers in patients with fatty liver and/or habitual alcoholic drinking. A: Serum angiotensin-converting enzyme (ACE) level; B: Aspartate aminotransferase to platelet index (APRI); C: Fibrosis index based on the four factors (FIB-4), D: Serum Mac-2 binding protein glycosylation isomer (M2BPGi) level in chronic hepatitis B patients with and without fatty liver and/or habitual alcoholic drinking (FL/AL). Serum ACE levels were significantly higher in the patients with FL/AL than those without FL/AL; E: Fibrosis stage-matched comparison showed that this difference in serum ACE levels between with and without FL/AL was prevalently observed in early stages (F0 and F1) of liver fibrosis. Data are means ± SD, ^bP < 0.01.