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©The Author(s) 2017.
World J Gastroenterol. Aug 7, 2017; 23(29): 5412-5421
Published online Aug 7, 2017. doi: 10.3748/wjg.v23.i29.5412
Published online Aug 7, 2017. doi: 10.3748/wjg.v23.i29.5412
Table 4 Serum level of bacterial translocation and enterocyte damage markers according to the different serologic antibody statuses
| Anti-F-actin IgA | Anti-F-actin IgG | Anti-gliadin IgA | Anti-gliadin IgG | |||||||||
| Negative (n = 48) | Positive (n = 19) | P value | Negative (n = 50) | Positive (n = 17) | P value | Negative (n = 61) | Positive (n = 6) | P value | Negative (n = 53) | Positive (n = 14) | P value | |
| Median, IQR | ||||||||||||
| LBP (μg/L) | 7132 (5150-9806) | 7374 (4348-12100) | 0.931 | 7377 (5795-9880) | 6847 (3828-13300) | 0.852 | 6959 (5044-9806) | 11450 (5836-15200) | 0.239 | 6959 (4951-9806) | 8090 (6077-12700) | 0.274 |
| EndoCab IgA (U) | 58 (40-92) | 123 (93-215) | < 0.001 | 68 (49-97) | 113 (52-150) | 0.195 | 70 (43-106) | 134 (66-241) | 0.079 | 70 (43-112) | 94 (52-150) | 0.301 |
| OMP Plus IgA, n (%) | 5 (10.60) | 7 (36.80) | 0.012 | 11 (22) | 1 (6.30) | 0.155 | 12 (20) | 0 (0) | 0.226 | 11 (21.20) | 1 (7.10) | 0.228 |
| I-FABP (pg/mL) | 166 (90-365) | 365 (203-1079) | 0.011 | 199 (143-513) | 300 (90-365) | 0.794 | 216 (99-443) | 342 (143-942) | 0.642 | 195 (99-379) | 342 (179-1020) | 0.092 |
- Citation: Tornai T, Palyu E, Vitalis Z, Tornai I, Tornai D, Antal-Szalmas P, Norman GL, Shums Z, Veres G, Dezsofi A, Par G, Par A, Orosz P, Szalay F, Lakatos PL, Papp M. Gut barrier failure biomarkers are associated with poor disease outcome in patients with primary sclerosing cholangitis. World J Gastroenterol 2017; 23(29): 5412-5421
- URL: https://www.wjgnet.com/1007-9327/full/v23/i29/5412.htm
- DOI: https://dx.doi.org/10.3748/wjg.v23.i29.5412