Observational Study
Copyright ©The Author(s) 2017.
World J Gastroenterol. Jul 28, 2017; 23(28): 5216-5228
Published online Jul 28, 2017. doi: 10.3748/wjg.v23.i28.5216
Table 8 Comparison of gastroesophageal reflux and dyspepsia-therapeutic efficacy and satisfaction test scores between responders and non-responders based on a "numeric rating scale ≤ 5" definition
Before Tx
After 4 wk PPI Tx
Δ (0W-4W)
Responder definition byResponder (n = 176)
Non-responder (n = 19)
Cohen's dP valueResponder (n = 176)
Non-responder (n = 19)
Cohen's dP valueResponder (n = 176)
Non-responder (n = 19)
Cohen's dP value
NRS 5 ≥meanSDmeanSDmeanSDmeanSDmeanSDmeanSD
Q1. Heartburn3.681.323.110.990.450.0221.690.892.371.300.730.027-1.991.42-0.741.150.90< 0.0001
Q2. Acid regurgitation3.191.372.951.22-0.4231.560.842.321.160.870.006-1.631.39-0.630.830.75< 0.0001
GERD-SS3.431.213.031.02-0.1061.620.812.341.210.850.012-1.811.27-0.680.870.91< 0.0001
Q3. Epigastric pain or burning3.081.383.111.41-0.9401.660.952.371.210.730.014-1.421.40-0.741.370.490.040
Q4. Postprandial fullness3.041.353.001.25-0.8961.901.052.421.120.500.053-1.141.32-0.581.170.430.051
Q5. Early satiation2.221.332.321.29-0.7531.690.892.260.930.640.012-0.531.06-0.051.030.450.058
FD-SS2.851.132.881.02-0.8991.730.822.360.820.770.002-1.131.08-0.530.830.570.004
Q6. Eating1.941.051.890.99-0.8411.350.691.630.680.400.095-0.590.92-0.260.810.360.101
Q7. Sleeping2.101.052.211.08-0.6791.230.551.841.011.020.010-0.881.00-0.370.900.510.022
Q8. Daily activity1.971.012.000.94-0.8811.260.591.950.911.100.001-0.711.04-0.050.400.67< 0.0001
Q9. Mood2.551.082.420.84-0.5341.510.782.050.850.700.008-1.051.08-0.370.500.65< 0.0001
Dissatisfaction for daily life-SS2.130.832.130.84-0.9891.340.531.870.770.950.004-0.810.78-0.260.430.73< 0.0001
Effect sizeSmallMediumLarge
Cohen's d0.2 ≤0.5 ≤0.8 ≤