Distinct gut microbiota profiles in patients with primary sclerosing cholangitis and ulcerative colitis

Table 2 Statistical expression of relative abundances disruption in the study groups at genus level

Genus	PSC	PSC-IBD	UC
Rothia	↑↑↑	↑↑	NS
Enterococcus	↑↑↑	↑↑	NS
Streptococcus	↑↑	↑↑	NS
Clostridium	↑↑	↑	NS
Veillonella	↑	↑	NS
Haemophilus	↑	↑	NS
Staphylococcus	NS	↑	NS
Coprobacillus	NS	↑	NS
Escherichia	NS	↑	NS
Corynebacterium	NS	↑	NS
Lactobacillus	NS	↑	NS
Coprococcus	↓↓	↓↓	↓↓
Phascolarctobacterium	NS	↓↓	↓↓
Akkermansia	NS	NS	↓↓↓
Roseburia	NS	NS	↓

Only taxa with P < 0.05 in at least one group are presented. ↑↑↑, ↓↓↓: Increased, decreased with P < 0.001; ↑↑, ↓↓: P < 0.01; ↑, ↓: P < 0.05; NS: Non-significant; PSC: Primary sclerosing cholangitis; IBD: Inflammatory bowel disease; UC: Ulcerative colitis.