miR-382 functions as a tumor suppressor against esophageal squamous cell carcinoma

Figure 3 miR-382 induced cell cycle arrest at G2/M phase in Eca109 cells. A and B: Cell cycle distribution of miR-382 overexpressed Eca109 cells and control cells was analyzed by flow cytometry at post-culture 48 h; C: Relative cell distribution percentage of LV-miR-382 expressed Eca109 cells to LV-Con control cells in each cell cycle phase. The data presented is mean ± SD of three independent experiments. ^aP < 0.05, vs control; D: Protein expression level of p21Cip1/Waf1 was examined in LV-Con Eca109 cells and LV-miR-382 Eca109 cells. β-actin was as a loading control.