Role of non-steroidal anti-inflammatory drugs on intestinal permeability and nonalcoholic fatty liver disease

Table 1 Occurrence of main adverse effects of non-steroidal anti-inflammatory drugs in the lower gastrointestinal tract with non-steroidal anti-inflammatory drug use

Adverse effect	Frequency
Increased gut permeability	44%-70%
Gut inflammation	60%-70%
Blood loss and anemia	30%
Malabsorption	40%-70%
Mucosal ulceration	30%-40%
Protein loss	10%
Mucosal ulceration	30%-40%
Complications requiring hospitalizations	0.3%-0.9%
Diaphragms of the small bowel	< 1%

Table constructed using data from[2,3,5].