Saccharomyces cerevisiae CNCM I-3856 in irritable bowel syndrome: An individual subject meta-analysis

Figure 1 Area under the curve (W0-W8) (A) and area under the curve (W5-W8) (B) of abdominal pain/discomfort in intent to treat population (all irritable bowel syndrome subtypes) and in irritable bowel syndrome-C subjects with an abdominal pain/discomfort score higher than or equal to 2 at baseline (irritable bowel syndrome-C ≥ 2) under placebo (white) or Saccharomyces cerevisiae CNCM I-3856 (grey) supplementation. Significant differences compared to placebo are symbolized by ^aP < 0.05. IBS-C: Irritable bowel syndrome-C; a.u.: Arbitrary unit; ITT: Intent to treat; AUC: Area under the curve.