Early complications after interventions in patients with acute pancreatitis

Table 3 Factors predicting progressive sepsis

Factors	P1value	Odd ratio(lower-upper)	P2value
Onset of symptoms to the first intervention
< 2 wk	0.093
2-4 wk	0.938
> 4 wk	0.176
APACHE-II score at admission	0.150
Marshall score at admission	0.015	1.723 (1.526-2.995)	0.046
Preoperative Marshall score	0.042	0.885 (0.607-1.290)	0.524
SIRS at admission	0.076
Preoperative SIRS	0.001	0.644 (0.210-1.976)	0.442
Single organ failure at any time before surgery	0.510
MOF at any time before surgery	0.041	2.031 (3.410-10.054)	0.038
CRP at admission	0.600
CRP before surgery	0.172
Morphological criteria on CECT
Pancreatic necrosis	0.157
Extrapancreatic necrosis	0.157
Percentage of necrosis
< 30%	0.157
30%-50%	0.526
> 50%	0.245
Gas bubble signs	0.351
CTSI before surgery	0.030	1.063 (0.811-1.393)	0.66
Infected pancreatic necrosis	0.274
Sepsis before surgery	0.0001	11.165 (5.384-23.153)	0.0001
Preoperative respiratory infection	0.0001	4.304 (2.085-8.884)	0.0001
Operation type	0.082

P₁ indicated two-sided P value of univariate analysis; P₂ indicated two-sided P value of multivariate analysis. APACHE: Acute physiology and chronic health examination; ICU: Intensive care unit; CRP: C-reactive protein; MOF: Multiple organ failure; CECT: Contrast-enhanced computed tomography; CTSI: Computed tomography severity index; SIRS: Systemic inflammatory response syndrome.