Copyright
©The Author(s) 2016.
World J Gastroenterol. Feb 21, 2016; 22(7): 2284-2293
Published online Feb 21, 2016. doi: 10.3748/wjg.v22.i7.2284
Published online Feb 21, 2016. doi: 10.3748/wjg.v22.i7.2284
Table 3 Frequently altered genes in esophageal squamous cell carcinoma
| Gene symbol | TP53 | NOTCH1 | PIK3CA | CDKN2A | CCND1 | FAT1 |
| Chromosomal location | 17p13.1 | 9q34.3 | 3q26.3 | 9p21.3 | 11q13 | 4q35.2 |
| Alteration frequency (%) | ||||||
| Agrawal et all[31] | 92 (M) | 33 (M) | 0 (M) | 8 (M) | NA | 8 (M) |
| Song et al[34] | 83 (M) | 9 (M) | 5 (M) | 5 (M) | 46 (G) | 5 (M) |
| 1 (L) | 41 (G) | 44 (L) | ||||
| Lin et al[33] | 60 (M) | 8 (M) | 7 (M) | 3 (M) | 46 (G) | 12 (M) |
| 10 (G) | 33 (L) | |||||
| Gao et al[32] | 93 (M) | 14 (M) | 9 (M) | 8 (M) | 33 (G) | 11 (M) |
| 2 (G) | 12 (L) | |||||
| Zhang et al[35] | 88 (M) | 21 (M) | 17 (M) | 8 (M) | 64 (G) | 15 (M) |
| 64 (L) |
- Citation: Sasaki Y, Tamura M, Koyama R, Nakagaki T, Adachi Y, Tokino T. Genomic characterization of esophageal squamous cell carcinoma: Insights from next-generation sequencing. World J Gastroenterol 2016; 22(7): 2284-2293
- URL: https://www.wjgnet.com/1007-9327/full/v22/i7/2284.htm
- DOI: https://dx.doi.org/10.3748/wjg.v22.i7.2284